摘要
对60例抗-HCV阳性患者的家庭成员124人进行血清学检测,并收集40例乙肝患者的家庭成员83人为对照.结果丙肝组检出抗-HCV阳性的家庭成员9人,检出率7.3%.除去有供血史的抗-HCV阳性家庭成员,检出率为1.85%(2/108).乙肝组未检出抗-HCV阳性者.在单一丙肝家庭组中,家庭成员的HBV感染率为25.33%,而在HBV/HCV重叠感染和HBV感染组的家庭成员中,HBV的感染率为40.91%,故提示,HCV的家庭内聚集性感染的危险性远低于HBV,且母于垂直传插的危险性更低于夫妻间水平传播.
To clarify the intrafamilial trasmission ofHCV infection,the antibody to HCV wasassayed in 124 serum samples from the familymembers of 60 HCV-Ab(+)index cases(groupc),and compared with that from 83 familymembers of 40 HCy-Ab(-)index patientswith hepatitis B(group B). Nine of 124,including 2 parents, 6 spouse and 1 grand-danghter, were positive for anti-HCV.Theprevalence of anti-HCV was 7.3%(9/124)intotal, and 1.85%(2/108)in the subjects who hadno history of blood donation. None of 83 waspositive for anti-HCV in group B.On the otherhand,the praralence of HBV infection was25. 33%in the group of HCV infection only, and40.91% in the group with HBV/HCV double-infection or HBV infection,It indicates thatthe risk of HBV intrafamilial trasmission ishigher than that of HCV,and the risk oftrasmission of HCV from mather to infant maybe lower than that of sexual trasmission.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
1994年第1期34-37,共4页
Chinese Journal of Epidemiology
基金
"八五"国家医学科技攻关
关键词
丙型肝炎病毒
乙型肝炎病毒
血清学
Hepatitis C virus(HCV)Hepatitis B virns(HBV)Intrafamilial transmission