摘要
对我院院龄1~4年的315名工作人员进行HBV-M调查中,发现显性乙肝患者12例(3.8%)、隐性乙肝感染者126例(40%),共138例(43.8%)。其中HBsAg阳性20例(6.3%)、抗-HBc阳性27例(8.6%)、抗-HBs阳性91例(28.9%)。提示乙肝对医务人员健康有严重的威胁;但手术科室与非手术科室、血库、检验人员与其他科室人员的感染率无明显差异。对HBV-M均阴性的177例进行了血源性乙肝疫苗接种,注射第三针后,抗-HBs阳转158/173例(91.3%),认为我国血源乙肝疫苗使用安全且有良好的免疫效果。
An epidemiological study on HBV infection among 315 staff of PUMC Hospital was carried out with detection of HBsAg,anti-HBs and anti-HBc by ELISA.The resulls showed that 138 persons had one or more markers of HBV infection and an overall HBV prevalence rate 43.8%.The positive rates of HBsAg anti-HBs,anti-HBc uere 6.3%,28.9% and 8.6%,respecti- vely.This indicates that HBV infection is a risk factor for medical staff,but there was no significant difference among medical,surgical and other members.In 1992,177 workers whose HBV markers were negative received 3 doses of HB vaccine at 0,1 and 6 months,resnpectively.91.3percent of them showed an anti-HBs response one month after the last inoculation.The result shows that our national made HB vaccine is safe and immunogenic.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
1994年第3期165-166,共2页
Chinese Journal of Epidemiology