大连地区不同人群军团菌感染的比较研究

Comparative Study on Legionella Infec-tion in Different Groups of Population in Dalian Area

笔者采用微量凝集试验对３００名健康献血员、１２０名非肺炎免疫功能低下的住院病人及１５８名（７４名双份血清）肺炎病人血清三种（１０型）军团菌抗体进行了检测。结果表明，大连地区存在所测三种（１０型）军团菌感染。三组人群各型之间抗体阳性率及ＧＭＴ均有显著性差异，均以Ｌｐ６最高，Ｌｐ１、Ｌｐ８次之。Ｌｐ１、Ｌｐ２、Ｌｐ６、Ｌｐ８抗体阳性率及ＧＭＴ在三组人群之间有显著性差异，肺炎组最高，非肺炎免疫功能低下组次之。提示大连地区军团菌感染以Ｌｐ６、Ｌｐ１、Ｌｐ８为优势种型，人群中隐性感染、亚临床感染和军团菌肺炎同时存在。

Using a microagglutination test,the prevalence of antibodies against three species(10 groups)of Legionella was determined in 300 healthy donors,120 non-pneumonic patients with immunodeficiency and 158 patients with pneu-monia. The results showed that there were sig-nificant differences among all groups on posi-tive rate and GMT in three groups.Lp6 was the highest,Lp1 and Lp8 came second.There were significant differences among three groups in positiv rate and GMT to Lp1,Lp2,Lp6 and Lp8,in the group of patiens with pneumonia was highest, the group of non-pneumonic pa-tients with immunodefieiency was second and healthy group was the lowest. It was suggested that the infection with Lp6,Lp1,Lp8 was predominant in population in Dalian area. The latent infection,subclinical infection and le-gionella pneumonia in population might be existance simulstaneously. Using test-tube agg-lutination, the paired sera collecoed from 74 pneumonic patients were studied,it was sho-wed that 5.4% of admitted pneumonic patients was legionellosis.