乙肝疫苗接种前筛检指标的探讨

A Study on Serologic Markers for Screen-ing before Hepatitis B Vaccination

目前乙肝疫苗接种前要进行ＨＢｓＡｇ、抗－ＨＢｓ和抗－ＨＢｃ三项指标的筛检。为了节省检验费用，并能达到一定的预防效果，我们对八个城市的乙肝感染情况进行了分析，在常规筛检时，只需筛检一项抗－ＨＢｃ。新生儿和０～３岁幼儿可以直接接种。这样，即能节省费用又能达到一定预防效果，符合费用－效果原则。

hree serologic markers for screening beforehepatitis B vaccination were HBsAg,anti-HBsand anti-HBc. The data of HB virus infectionin eight cities were analysed in order to savetest cost and to achieve similar immune effect. For routine screening, anti-HBc is the only onemarker needed to be used. The neonates and chil-dren aged 0～3 years can be vaccinated directly without screening.