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国产重组人粒细胞集落刺激因子在儿童急性白血病中的疗效评价 被引量:1

Evaluation of the therapeutic effect of domestic rhG-GSF on children’s acute leukemia
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摘要 目的:评价国产与进口重组人粒细胞集落刺激因子(rhG鄄GSF)治疗儿童急性白血病化疗后白细胞降低的临床疗效。方法:将急性白血病患儿随机分成治疗组和对照组,化疗结束48h后,当WBC<2.0×109/L或ANC<1.5×109/L时开始用药,治疗组使用国产rhG鄄GSF,对照组使用进口同类产品。结果:两组总有效率比较无显著性差异(P>0.05)。结论:国产rhG鄄GSF在促进粒细胞恢复上的治疗效果完全可以达到进口同类产品水平。 Objective:To evaluate the clinical efficacy in raising the count of leukocytes by using domestic rhG-GSF and compare it with that of the similar imported product.Methods:Children suffering from acute leukemia were randomly divided into treating group and control group.48hours after the chemotherapy and when WBC<2.0×10 9 /L or ANC<1.5×10 9 /L were reached,the patients began to be treated with domestic rhG-GSF and its congeneric imported drugs respectively.Result:The total effective rates of treating group and con-trol group were generally equivalent and no significant difference between them(P>0.05).Conclusion:As for the clinical efficacy in raising the count of leukocytes,the domestic rhG-GSF can achieve the same level of its congeneric import drugs.
作者 林雪峰
出处 《儿科药学杂志》 CAS 2003年第4期38-39,共2页 Journal of Pediatric Pharmacy
关键词 儿童 急性白血病 重组人粒细胞集落刺激因子 Children’s Acute leukemia Recombination human granulocyte colony stimulating-factor
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