阿替洛尔治疗卧位型心绞痛疗效观察

Curative Observation on Atenolol in Treatment of Angina Decubitus

目的 探讨卧位型心绞痛的有效治疗。方法 选择卧位型心绞痛患者 17例 ,在常规抗高血压、抗血小板聚集、降低血脂、扩血管药物治疗基础上 ,加用 β -受体阻滞剂阿替洛尔 4周 ,与 13例对照组进行临床疗效比较。结果 应用阿替洛尔治疗卧位型心绞痛效果显著 ,四周有效率为 94 .12 % ,与对照组比较差异显著 (P <0 .0 1)。结论 阿替洛尔通过选择性阻断 β1受体 ,减慢心率 ,降低心肌耗氧量 ,使缺血区心肌得到更多的血液供应 ,治疗卧位型心绞痛效果显著。

Objective To study the effective treatment of angina decubitus.Methods 17 patients with unsatisfactory results of previous ordinary therapy took β-receptor blocker Atenolol during the conventional treatments with antihypertensive, antiplatetet,antilipemic and vasodilator.Four weeks later,the curative effect was compared with data from 13 cases of the control group.Results The clinical symptoms of patients with angina decubitus who received Atenolol were improved significantly.The effective rate was 94.12%. There was significant difference compared with the control group (P<0.01).Conclusion β-receptor blocker Atenolol may significantly improve the clinical symptoms of patients with angina decubitus.