1Kanamori Y,Kigawa J,Itamochi H,et al.Correlation between loss of PTEN expression and Akt phosphorylation inendometrial carcinoma.Clin Cancer Res.2001 Apr;7(4):892-5.
2Li DM,Sun H.PTEN/MMAC1/TPE1 suppresses the tumorig-enicity and induces G1 cell cycle arrestin human glioblastoma cells.Proc Natl Acad Sci USA.1998 Dec 22;95(26):15406~10411.
3Davies MA,Lu Y,Sano T,et al.Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Aktactivation and induces anoikis.Cancer Res.1998 Dec 1;58(23):5285-90.
4Li J,Simpson L,Takahashi M,The PTEN/mMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.Cancer Res.1998 Dec 15;58(24):5667-25722.
5Zundel W,Schindler C,Haas-Kogan D,et al.Loss of PTEN facilitates HIF-1-lmediated gene expression.Genes Dev.2000 Feb 15;(4)319-326.
6Di Cristofano A,Pesce B,Cordon-Cardo C,Pandolfi PP.Pten is essential for embryonic development and tumour suppression.Nat Genet.1998 Aug;19(4):348~355.
7Cantley LC,Neel BG.New insights into tumor suppression:PTEN suppresses tumor formation by restraining the phosphoinostide 3-kinase/AKT pathway.Proc Natl Acad Sci U S A,1999,96(8):4240~4245.
8Lachyankar MB,Sultana N,Schonhoff CM,et al.A role for nuclear PTEN in neuronal differentiation.J Neurosci,200020(4):1404~1413.
9Risinger JI,Hayes AK,Berchuck A,Barrett JC.PTEN/MMAC1 mutations in endometrial cancers.Cancer Res.1997 Nov 1;57(21):4736~4738.
6Kitaoka H, Hitomi N, Yabe T, et al. Cardiovascular events and plasmaatrial natriuretic peptide level in patients with hypertrophic car- diomyopathy[J]. Am J Cardio!, 2001,87(3) : 1318-1320.
7Stanton H C, Brener G, Mayfield E W. Studys on isoproternol-induced cardiomegaly rat[J]. Am Heart J, 1969,77 ( 1 ) : 72-80.
8Nirmala C,Puvanakrishman R. Protective role of curcumin against isoproterenol-induced myocardial infarction in rats[J]. Mol Cell Bio chem,1996,159(2):85.
9Sehwartzbauer G, Robbins J. The tumor supp ressor gene PTEN can regulate cardiac hypertrohy and survival[J]. J Biol Chem,2005,276 (5) :3,5786.
10Bepler G, Sharma S, Cantor A, et al. RRM1 and PTEN as prognostic parameters for overall and disease-free survival in patients with non-small-cell lung cancer[J]. J Clin Oncol, 2004,22(10): 1878-1885.