摘要
医源性骨质疏松是一种较常见的继发性骨质疏松,见于长期大量应用糖皮质激素治疗的病人,本文中6例分别为支气管哮喘2例、类风湿性关节炎2例、皮肤病1例、胶原病1例,男女各3例,年龄29~46岁,糖皮质激素治疗原发病期限1~3.5年,平均1.56年,除1例用氟美松(每日0.75g)外,余5例均用泼尼松(每日15~30mg)经过改用激素隔日疗法,加用钙剂、维生素D,随访1年,6例患者矿物质含量增加,生化指标好转。
atrogenic osteoporsis is a very common seeondory osleoporosis is found in patients treated with large dosage of glucocortieosteroid of long duration,Six cases listed in this article including 2 cases of bronchial asthma,2 cases of bronchial asthma,2 cases of rheumatoid arthitis,1 case of skindiesase and 1 case of callagenosis(three male patients and three female patients).The age is from 27- 46.The dura-tion of treatmert of primary disease with glucocortieosteroid is 1 to 3.5 years,with the average of 1.56 years.With the exception of one case treated with Dexamethasone one of 0.75g daily, the other 5 cases are treated with predinisone of 5-30mg daily. After they treated with hormone every other day and added Calcium and vitamin D and follewed up 1 year, the mineral contents in the bone of all 6 patients are increased and the biochemistry indexes are improved.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1994年第10期658-660,共3页
Chinese Journal of Internal Medicine