持续灌流法经皮冠状动脉球囊成形术的临床价值

THE CLINCAL VALUE OF CONTINUOUS PERFUSION PERCUTANEOUS TRANSLUMINAL CORO-NARY ANGIOPLASITY IN TREATMENT OF CORONARY ARTERY DISEASE

对２２例冠心病患者行持续灌流法经皮冠状动脉球囊成形术（ＣＰＰＴＣＡ），对另２０例行常规冠状动脉球囊成形术（ＰＴＣＡ）。发现：ＣＰＰＴＣＡ组较ＰＴＣＡ组耐受更长的扩张时间，且充盈球囊后出现心绞痛的时间和心电图缺血样改变的时间均较ＰＴＣＡ组延后，室速、室颤及低血压发生率明显少于后者，残余狭窄、残余跨狭窄压差、再狭窄率显著低于后者。但两组间再梗塞及１年死亡率无显著不同。

ourty two patients with coronary artery disease were studied. Among them 22 were treated with continuous perfusion percutaneous transluminal coronary angioplasty(CPPTCA)and 20 with percutaneous transluminal coronary angioplasty(PTCA). It was found that patients treated with CPPTCA can stand longer time of dilatation during operation than those treated with PTCA (P<0.01).Moreover,angina pectoris and ischemic changes of ECG occurred later during CPPTCA than during PTCA(P< 0. 001)。The incidences of ventricular tachycardia,ventricular fibrillation,residual transstenosis pressure gradient and residual stenosis were all lower in patients treated with CPPTCA than those with PTCA(P<0. 01～0.001).However, there was no significant difference in the incidence of reinfarction and one-year mortali-ty between the patients after CPPTCA and PTCA.