溶血磷脂制备含胆固醇微乳液的研究

Study on the Microemulsion of Lysolecithin Containing Cholesterol

溶血磷脂HLB较大,易形成O/W型乳化剂,可制备热力学稳定的微乳化体系。利用溶血磷脂作乳化剂,制备含胆固醇的微乳液,是以胆固醇为油相,溶血磷脂为乳化剂,正丙醇为共表面活性剂,制成微乳液。最终产物呈透明或半透明的均相混合物。

Lysolecithin having bigger HLB, can form system O/W easily, which is thermodynamically stable colloidal system. Preparing system of lysolecithin-based microemulsion containing cholesterol, was made up of cholesterol / lysolecithin / n- propanol, lysolecithin as emulsifier, n-propanol as co-surfactant, cholesterol as oil phase. It was show that the microemulsions are clear, transparent, stable.