治疗牙周炎对老年2型糖尿病患者糖化血红蛋白的影响

The effect of periodontal therapy on glycosylated hemoglobin in elderly patients with type 2 diabeties and periodontitis

目的观察牙周基础治疗对老年2型糖尿病伴牙周炎患者的糖化血红蛋白(glycosylatedhemoglobin,HbAIc)水平的影响。方法选择门诊治疗中伴牙周炎的老年2型糖尿病患者,根据患者的病情和要求分为牙周治疗组和不做牙周治疗的对照组各20例。治疗组给予牙周基础治疗,记录牙周治疗组治疗前和治疗后4、12、24周时的牙周探诊深度(probingdepth,PD),出血指数(bleedingindexBI),菌斑指数(plagueindex,PLI)和HbA1c的情况;对照组于入选时及入选后24周观察上述指标。结果牙周治疗组于治疗后4、12、24周时各项牙周临床指标均有下降,与治疗前比较,差异有统计学意义(P<0.01);该组HbA1c于治疗后12、24周时分别为(7.88±0.45)、(7.80±0.87)%,与治疗前(9.06±0.71)%比较,差异有统计学意义(P<0.01)。对照组各项牙周指标及HbA1c在24周内无明显变化(P>0.01)。结论对患有牙周炎的老年2型糖尿病患者,牙周基础治疗可改善牙周状况,降低HbA1c水平。

Objective To investigate the effect of periodontal initial therapy on the level of glycosy lated hemoglobin (HbA1c) of elderly patients with type 2 diabeties mellitus and periodontitis. Methods Forty elderly patients with type 2 diabeties mellitus and periodontitis were divided into two groups: periodontal therapy group and control group depend on their demands and situation. The periodontal therapy group received initial therapy,the periodontal clinic index(probing depth, bleeding index, plaque index)and HbA1c were determined before treatment and at 4 weeks, 12 weeks,24 weeks after treatment. The control group did not received any periodontal therapy, the periodontal clinic index and HbA1c were determined at begining and 24 weeks after treatment. Results After initial therapy, all periodontal clinic index at 4, 12, 24 weeks after treatment were reduced significantly(P<0.01), HbA1c at 12,24 weeks after treatment were (7.88±0.45)、(7.80±0.87)%, as comparand to (9.06±0.71)% before treatment, were reduced significantly too(P<0.01). While in control group,there were no significantly differences in all periodontal clinic index and HbA1c(all P>0.01). Conclusions The result of periodontal initial therapy in aged type 2 diabetic patients with periodontitis is satisfied , it can improve periodontal conditions and also can reduce the level of HbA1c of patients.