2型糖尿病患者合并脂肪肝的临床分析

The clinical analysis of type 2 diabetes mellitus patients with fatty liver

目的探讨2型糖尿病患者脂肪肝和胰岛素抵抗、体重指数、血糖、血脂、血压的关系。方法采用病例对照研究,分两组,①2型糖尿病合并脂肪肝组;②2型糖尿病不伴脂肪肝组做对照。进行体重指数(BMI)、血脂、空腹和餐后2小时血糖(2hPBG)、胰岛素抵抗指数(HOMA-IR)的比较。结果2型糖尿病合并脂肪肝组的体重、BMI,舒张压、餐后2小时血糖、总胆固醇、甘油三酯、HOMA-IR明显高于2型糖尿病对照组(P<0.05)。结论TC,TG,HOMA-IR,BMI,LDL和糖尿病脂肪肝的形成有关。脂肪肝形成危险因素的Logistic回归分析,体重、2hPBG是2型糖尿病脂脂肝形成的最主要的危险因素。

Objective To explore the relationship between fatty liver and insulin resistance,and BMI in type 2 diabetes mellitus.Method The investigation was conducted by virtue of case-control study,that is ,one group was made of type 2 diabetes patients with fatty liver,and the other one consisted of type 2 diabetes patients without fatty liver as control group.BMI,serum lipids,fasting and 2-hour postprandial serum glucose,HOMA-IR,were measured in all the patients.Result Body weight,BMI,diastolic blood pressure,2-hour postprandial serum glucose,serum cholesterol,serum triglceride,and HOMA-IR were higher in patients with type 2 diabetes mellitus with fatty liver group than control group.Conclusion TC,TG,HOMA-IR,BMI and LDL are connected with the diabetes mellitus with fatty liver,and what's more,body weight and 2-hour postprandial serum glucose are the risk factors of fatty liver.