外源性糖对变形链球菌活性氧代谢的作用

Effect of extraneous sugar on the reactive oxygen species metabolism of strept ococcus mutans

目的:研究外源性糖对变形链球菌活性氧代谢的作用,探讨外源性糖及变形链球菌活性氧代谢对菌斑微生态的作用。方法:采用电子自旋捕捉法(electronspinresonance, ESR)检测不同糖培养条件下变形链球菌产生活性氧的情况。结果:随着糖浓度的提高,变形链球菌产生活性氧的量增加;外源性糖溶液培养时间在2h以内,变形链球菌产生活性氧的量最多;不同类型糖均促进变形链球菌产生活性氧。结论:外源性糖促进变形链球菌活性氧代谢。

Objective:To study the effect of extraneous sugar on rea ct ive oxygen species metabolism of Streptococcus mutans. Methods: Electron spin resonance (ESR) method was used to measure reactive oxygen spe cies of Streptococcus mutans incubated in the different sugar incubation con ditions. Results:With the increase of glucose at 0.0062~0.05 mo l/L, the quantities of reactive oxygen species produced by Streptococcus mutan s increased and increased to the maximum when Streptococcus mutans were in cubated in different sugar culture fluids within 2 h. All kinds of sugar promote d reactive oxygen species metabolism of Streptococcus mutans. Conclu sion:Extraneous sugar promotes reactive oxygen species metabolism of Streptococcus mutans.