血清胰岛素与胆囊结石关系的研究

Study in the relation between serum in-sulin and gallbladder stone disease

本文测定了２６例胆囊结石患者及２０例对照组的血清胰岛素的含量，并同时测定了胆囊结石患者胆汁中主要酯类的浓度。结果发现胆囊结石患者的血清胰岛素的含量显著高于对照组。其胆汁中胆固醇呈过饱和状态，血清胰岛素与胆汁中胆固醇及成石指数呈显著正相关。结果表明，胰岛素可提高胆汁中胆固醇的饱和指数，促进胆固醇析出形成结石。

Abstract Serum insulin was measured in 26 pa-tients with gallbladder stone disease and con-trols,biliary mian lipid compositions weremeasured in patients too.The results showedthat,compared with the controls,the patientswith gallbladder stone have significantly high-er level of serum insulin,Patients biliarycholesterol present supersaturated condition. Serum insulin show a positive significantlycorrelation with biliary cholesterol andLithognic index. as indicate above,the increasein the level of serum insulin in pat ients withgallblader stone can raise biliary saturated de-gree and promoe the growth of gallstone.