摘要
本研究用脾细胞分泌白细胞介素２和ＮＫ活性作为免疫功能检测，观察了ｔｕｆｔｓｉｎ对荷肝癌小鼠免疫功能及生存期的影响，探讨了ｔｕｆｔｓｉｎ的抗肿瘤作用及其机理，结果表明ｔｕｆｔｓｉｎ可提高荷癌小鼠的免疫功能，延长生存期，并提示其提高脾细胞分泌ＩＬ－２和增强脾细胞的ＮＫ活性是ｔｕｆｔｓｉｎ抗肿瘤的机理之一。
The effect of tuftsin on the immune
func-tion of hepatic carcinoma-bearing mice was ob-served through measure of secretion of
inter-leukin2(IL-2)and activity of NK of spleniccells,the antitumor effect and mechanism oftuftsin
was studied.The results show that theimmune function of tumor-bearing mice wasenhanced and
their survival period was pro-longed by tuftsin. Results suggest that it isone of the antitumor
mechanism of tuftsin toincrease the secretion of IL-2 of splenic cellsand enhance the activity of NK
of the cells.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
1994年第6期345-346,共2页
Chinese Journal of Experimental Surgery
