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大鼠液压颅脑伤后血糖、脑脊液乳酸和局部脑血流的改变 被引量:3

A fluid percussion model of brain injutyin rats:alterations of biochemistry and regional cerebral blood flow
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摘要 30只大鼠经液压装置致中度液压颅脑损伤,伤后1小时有血糖和脑脊液乳酸的升高,9只大鼠中度液压颅脑伤后即刻有短暂的血压升高和心率加快,并通过颅骨窗用激光多谱勒技术发现有伤后早期的局部脑血流下降。 Abstract We characterized the biochemistry and fe-gional cerebral blood flow in rats produced bylateral fluid percussion head injury of midiumseverity. Biochemistry experiments in 30 ratsdemonstrated cerebal spinal fluid lactic acido-sis and hyperglycemia,Systemic hypertensionand bradycardia occured in 9 rats after fluidpercussion injury.A decrease in regional cere-bral blood flow measured by Laser-Dopplerwas observed.These results indicates fluid percussion model in the rat may therefore be auseful experimetal model for study of traumat-ic brain injury.
机构地区 解放军
出处 《中华实验外科杂志》 CAS CSCD 北大核心 1994年第6期353-354,共2页 Chinese Journal of Experimental Surgery
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