蝮蛇咬伤致急性肾功能衰竭48例报告

Acute renal failure caused by viper:report of 48cases

我院１９８４～１９９１年共收治蝮蛇咬伤４８６０例，其中伤后发生急性肾功能衰竭者４８例，４８例中，治愈４３例，死亡５例（１０．４％）。由于蛇毒对肾脏具有较大的直接毒性作用，加之血液毒所致之大量溶血，故伤后很快发生急性肾功能衰竭。及时病因治疗，碱化尿液，必要时进行腹膜透析，积极维持心肺肝等重要脏器的功能是提高治愈率的关键。

AbstractViper is common in China andits secretion is amixture consisting of both hemo-toxin and neuro-toxinthat cause acute renal failure and respiratory paralysis.In 4860 cases of snake-bites treated from 1984 to 1991,48(0.99%)resulted in acute renal failure. Aftertreatment, 43 cases were completely recovered and 5(10.4%)died of serious failure. Because the toxisityof viper directly attacks both kidenies and toxaemiamay cause massive hemolysis to rapidly develop acuterenal failure. Instant etiological treatment,alkalizationurine,peritoneal dialysis are necessary to sustain thefunction of heart,liver and lung.