摘要
为了探讨胆管空肠Ｒｏｕｘ－ｅｎ－Ｙ吻合术（ＣＪＲ－Ｙ）后继发性高胃酸分泌的机理，作者研究了ＣＪＲ－Ｙ术患者血、胃液、胃窦部粘膜组织内生长抑素（ＳＳ）、胃泌素（ＧＮ）、神经降压素（ＮＴ）、β－内啡肽（β－ＥＰ）的改变及胃酸分泌的变化。结果显示此术后发生了胃酸分泌；发现血、胃液及胃窦部粘膜组织内ＳＳ含量明显下降，Ｇｎ含量升高；ＮＴ和β－ＥＰ无明显变化。认为ＳＳ的改变是ＣＪＲ－Ｙ术后继发性高胃酸分泌的重要原因，并在此机理中起关键作用。
AbstractIn order to explore the mechanisTn of secondarygastric acid hypersecretion after Roux-en-YCholangio-jejunostomy (CJR-Y),we studied the changes of gas-tric acid secrelion and determined the levekof somato-statin(SS),gastrin(Gn),neurotensin(NT),β-endor-phin(β-EP) in serum , gastric juice and pyloric antrumin patients with CJR-Y,The results showed that gas-tric hypersecretion developed,levels of SS in thosespecimems decreased significantly and the content ofGnincreased obviouslv after CJR-Y;whereas the con-tent of NT andβ-EP did not change significantly.Weconcluded that the decreased level of SS plays a role inthe mechanism
出处
《中华外科杂志》
CAS
CSCD
北大核心
1994年第12期749-752,共4页
Chinese Journal of Surgery
