活化的扁桃体淋巴细胞上CD^（23）分子的表达

CD23 MOLECULAR EXPRESSION ON ACTIVATED HUMAN TONSIL LYMPHOCYTES

本文报道观察扁桃体单个核细胞、Ｔ淋巴细胞、Ｂ淋巴细胞经淋巴细胞活化剂ＰＭＡ、ＰＨＡ刺激４８小时后细胞膜表面ＣＤ２３分子的表达情况。实验表明上述细胞经活化后ＣＤ２３分子的表达均有不同程度的增高，以ＰＭＡ活化后的Ｂ淋巴细胞增高表达最明显，ＣＤ２３阳性率由活化前的２８．７６±３．１９％增高为３５．３４±２．３４％。Ｔ细胞经ＰＨＡ、ＰＭＡ活化后，ＣＤ２３表达也有微弱增高。

Choosing PMA,PHA as lymphocytes activator,we observed CD23 expression on activated mononuclearcells ,activated B cells and activated T cells from human tonsil.The results of FACS analysis showed that activatedB cells showed a significant higher CD23 expression,activated T cells only a little higher expression than the non-activated.The percentages of CD23 positive cells of PMA activated mononuclear cells,T cells and B cells were24.0±1.1%, 11.4±1.8%and 35.34±2.34%,and those of PHA activated were 21.95±1.15%, 9.9±1.5%,and30.85±2.12%,respectively.