摘要
将人工关节材料高密度聚乙烯粉末（ＨＤＰ），多聚甲基丙烯酸树脂（ＰＭＭＡ）和甲基丙烯酸树脂（ＭＭＡ）分别注入家兔膝关节内后３日至１２周取材，通过光镜和透射电镜进行组织学观察，并对它们引起的组织学反应进行比较．ＰＭＭＡ注射后的滑膜增生，肿胀明显，周围的组织学反应细胞大量浸润，较ＨＤＰ注射后的组织学反应明显（Ｐ＜０．０５）．而ＭＭＡ导致大片组织变性和坏死．ＰＭＭＡ和ＭＭＡ可能是导致人工关节松动的主要因素．
We investigated the reaction in bone,cartilage and synovium on 48 rabbit knee joints which were injected into with high density polyethylene(HDP),or polymethyl methacrylate powder(PMMA),or methyl methacrylate(MMA)or saline.The specimens were obtained at intervals from 3rd day to 12th week after injection. In PMMA group, the proliferation and hyperemia of synovium were apparent,and the involvement of large amounts of histological reaction cells showed high significant differences between it and HDP group. In MMA group, there were a lot of degeneration and necrosis of tissues.The results suggest that PMMA is one of factors provoking the histological reaction and MMA might be the main factor inducing prosthesis loosening.
出处
《中华物理医学杂志》
CAS
CSCD
1994年第3期132-134,196,共3页
Chinese Journal of Physical Medicine and Rehabilitation
关键词
人工关节
聚乙烯
组织学反应
prosthesis
polyethylene
bone cement
histological reaction
