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蛋白磷酸酶及其抑制剂研究近况 被引量:4

Recent development of studies on protein phosphatase and its inhibitors
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摘要 蛋白磷酸酶是一类在信号转导途径中起关键调节作用的酶家族,其缺失或功能失调可导致多种疾病的发生。近年来,国外学者关于蛋白磷酸酶及其抑制剂的研究颇多,并取得相当进展。现就此进行系统综述,以期把握蛋白磷酸酶及其抑制剂的作用、应用以及对进一步的相关研究提供参考。
作者 石继祥 施杞
出处 《国外医学(临床生物化学与检验学分册)》 2005年第5期281-284,共4页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
基金 国家自然科学基金资助项目(30371794)
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参考文献15

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  • 2Pearson G, Robinson F, Beers-Gibson T, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev, 2001, 22(2): 153-183.
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  • 8黄其擎,张鸿卿,薛绍白.三种蛋白磷酸酶抑制剂对A_(23187)诱导的HL-60细胞程序性死亡的影响[J].生物化学与生物物理学报,1996,28(5):562-567. 被引量:2
  • 9Klaman LD, Boss O, Peroni OD, et al. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol, 2000, 20(15): 5479-5489.
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二级参考文献2

  • 1N Zhiqiang,Eur J Immunol,1993年,23卷,3369页
  • 2Shi Y F,Nature,1989年,339卷,625页

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