多巴酚丁胺负荷超声心动图试验对冠心病诊断价值的评价

Diagnostic value of dobutamine stress echocardiography in coronary artery disease

以冠状动脉造影为标准，对３９例冠脉狭窄≥５０％的冠心病人与１３例冠脉狭窄＜５０％或腔径正常的临床可疑冠心病人作为＂正常＂对照，用多巴酚丁胺负荷超声心动图（Ｄｏｂｕ－Ｅｃｈｏ）和心电图（Ｄｏｂｕ－ＥＣＧ）试验对冠心病的诊断价值进行了评价。发现Ｄｏｂｕ－Ｅｃｈｏ的敏感性为９２．３％，特异性为８４．６％，准确度为９０．４％；而Ｄｏｂｕ－ＥＣＧ的敏感性为３０．８％，特异性７６．９％，准确度４２．３％。试验中未发现严重不良反应发生。结果认为：Ｄｏｂｕ－Ｅｃｈｏ是安全、准确性好的无创性冠心病诊断试验，可推广临床应用。

Abstract To estimate the diagnostic value of dobutamine stress echocardiography (Dobu-Echo) and electrocardiography (Dobu-ECG) in coronary artery disease (CAD), 52 cases presenting for coronary angiography (39 cases with CAD and 13 cases without CAD) were prospectively studied. The sensitivity of Dobu-Echo was 92.3%, specificity 84.6% and accuracy 90.4% while the sensitivity of Dobu-ECG was 30.8% , specificity 76.9% and accuracy 42.3 % . No major adverse effects was found during the tests. We conclude that Dobu-Echo is a safe and accurate test for noninvasive identifying CAD and can be used widely.