浅析脑胶质瘤病的MRI征象和临床表现

Diagnosis of gliomatosis cerebri with Magnetic Resonance signs and clinical manifestation

目的评价脑胶质瘤病的核磁共振成像(MRI)影像特征。方法回顾性分析6例经病理证实或临床随访的大脑胶质瘤病的平扫及增强核磁共振(MRI)影像资料,找出其中的特征性表现并与既往文献对照。结果6例患者MRI影像均显示双大脑半球多叶弥漫性病灶,边界不清,除1例外胼胝体均受累,1例侵犯脑干,3例侵犯外囊、基底节区。4例增强MRI无明显强化效应,2例可见多发局灶性结节样及环状强化。结论MRI对诊断大脑胶质瘤病有较大价值,应作为首选。

Objective To review the feature of magnetic resonance (MRI) in gliomatosis cerebri (GC) and its application in diagnosis. Methods The MRI manifestation of GC proven by pathological check and confirmed by following-up observation was analyzed retrospectively. The distribution and extent of lesion was assessed referring to literatures. Results MRI revealed diffuse lesion in both hemicerebrum without distinct borders. Tumor involved at least 2 lobes of the brain in all patients, with extension to callosum in 5,brain stem in 1,and basal ganglia in 3 cases of the 6. No marked enhancement were seen. Conclusion MRI examination plays an important role in detecting and localizing GC. It can be considered as one of the optimal diagnosis means of the disease so far.