心先安治疗心肌炎合并房室传导阻滞26例临床观察

Clinical Observation of Meglumine Adenosine Cyclophosphate on treatment of Myocarditis with Atrioventricular Block

目的探讨心先安治疗心肌炎合并房室传导阻滞的临床疗效。方法将52例心肌炎合并房室传导阻滞病人随机分为治疗组(26例)和对照组(26例)。对照组给予积极治疗原发病、休息、抗感染、营养心肌、激素及其他对症治疗;治疗组在其基础上加用心先安,疗程7天。分别观察两组治疗前后临床疗效和心电图的变化。结果临床疗效:治疗组和对照组总有效率分别是84.6%和50.0%,两组比较有非常显著性差异(P<0.01);体表心电图和24小时动态心电图:治疗组和对照组总有效率分别是76.9%和38.5%,统计学比较有明显差异(P<0.01)。结论心先安治疗心肌炎合并房室传导阻滞有较好的疗效,优于常规治疗,值得临床推广应用。

Objective To investigate the clinical effect of CAMPon the treatment of myocarditis with atri oventricular block. Methods Divided 52 myocarditis patients suffering from atrioventricular block into two groups : treament group(n=26)and control group(n=26).The control group received basic regular treatment such as primary disease treatment , rest, alimenting myocardium, hormone ,antiinfection and other heteropathy,while the treatment group took cAMPfor seven days with the basic regular treatment at the same time as control group.The clinical and ECGand cardiac Holter monitoring changes were observed during the treatment. Results The total clinical curative efficiency was 84.6% and 50.0% , in treatment group and control group respectively with significant difference(P<0.01);in addition ,ECG and24-hour Holter monitoring results also showed significant changes in treatment group and control group in curative effect,76.9%and 38.5%respectively(P<0.01).Conclusion CAMP has a better curative effect on treatment of myocarditis accompanying with atrioventricular block than regular treatment.