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非酒精性脂肪性肝病的临床特点和相关危险因素

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摘要 目的:探讨非酒精性脂肪性肝病(NAFLD)的相关危险因素和临床特点,为 NAFID 的早期诊断、预防、治疗提供科学的依据。方法:运用回顾性的病例对照研究,结合多元 Logistic 回归分析,探讨 NAFLD 的相关危险因素和临床特点。结果:BMI、舒张压、高脂饮食、甘油三脂(TG)、载脂蛋白 B(ApoB)等5个因素为 NAFLD 独立危险因素,高密度脂蛋白(HDL)为 NAFLD 的保护因素。NAFLD 组血清转氨酶异常率与对照组相比差别有统计学意义。重度脂肪肝与轻中度脂肪肝相比主要以转氨酶和尿酸(UA)的升高为主。肥胖、Ⅱ型糖尿病、心脑血管疾病、高脂血症等为 NAFLD 的伴发疾病。结论:控制体重,改变生活方式,定期体检为预防 NAFLD 的重要措施。
出处 《新疆医学》 2005年第3期5-8,共4页 Xinjiang Medical Journal
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