妇科与肺部非恶性疾病中CA125含量变化的探讨

Change of CA125 in nonmalingnant diseases

目的:探讨在非恶性疾病中cAl25舍量变化情况。方法:采用电化学发光方法检测血清中cAl25含量。结果:妇科良性疾病cAl25含量均比对照组高,但比卵巢癌患者含量低(P<0.01)。以子宫内膜异位症阳性率最高为100%,宫外孕阳性率最低为0;肺部良性疾病患者CAl25含量均比对照组显著升高(P<O.01),肺炎患者CAl25含量明显低于肺癌患者和结核(包括肺结核和结核性胸膜炎)患者。结论:非恶性痰病中CAl25含量升高,在临床诊断中应加以考虑。

Objective: To study the change of CA125 in the nonmalignant diseases. Methods : The serum level of CA125 was assayed by using electrochemiluminescence immunoassay. Results: The serum level of CA125 was significanflyy elevated in benign diseases of patients of department of genecology compared with the control group, but was significantly decreased compared with patients with ovarian cancer( P < 0. 01 ). The positive rate of adenomyosis was the highest ( 100% ). The positive rate of extrauterine pregnancy was the lowest(0% ). The serum level of CA125 was significantly el-evated in patients with benig diseases of lung compared with the control group( P < 0. 01 ). The CA125 level in patients with pneumonia was significantly decreased compared with that of lung cancer and tuberculosis, incluaing pulmonary tuber-culosis and tuberculous pleurisy. Conclusion:The level of CA125 in the no.malignant diseases was increased.