婴幼儿重症肺炎合并中毒性脑病的治疗分析

Analysis of the treatment of infant severe pneumonia with toxic encephalopathy

目的:探讨婴幼儿重症肺炎并发中毒性脑病的发病机制、临床表现及有效的辅助检查和治疗方法。方法:对28例婴幼儿重症肺炎并发中毒性脑病患儿的临床表现进行统计,110例重症肺炎患儿查血钠,经皮测血氧饱和度。结果:婴幼儿重症肺炎并发中毒性脑病的发生率为25.5%,氧饱和度越低,中毒性脑病的发生率越高,110例重症肺炎患儿,低钠血症发生率为56%。颅内高压是导致呼吸衰竭及脑疝而死亡的主要原因。结论:中毒性脑病是重症肺炎常见的并发症,中毒性脑病的发生与缺氧、低钠血症密切相关。控制颅内高压是治疗的重点。

Objectave To explore the etiology, clinical manifestations, essential laboratory findings and treatment of infants severe pneumonia with toxic encephalopathy. Methods To analyse the symptoms of all the 28 cases of severe pneumonia with toxic encephalopathy ,serum Na+ were examined while SPO2 was also detected through skin. Results Incidence of infants severe pneumonia with toxic encephalopathy was 25.5% in all the 110 cases .And it showed that the lower SPO2 associated with the higher incidence of toxic encephalopathy;the incidence of hyponatremia was 56%.High ICP was the main reason which resulted in respiratory failure and cerebral hernia to cause death. Conclusion Toxic encephalopathy is a common complication of severe pneumonia and its occurrence is closely associated with hypoxia and hyponatremia.The focus of treatment is to control high ICP.