PrP^C转化成PrP^(Sc)的影响因素研究进展
被引量:1
摘要
朊病毒蛋白有两种形式,即PrPC和PrPSc。PrPC是正常的细胞蛋白;而PrPSc是PrPC的异构体,具有致病性。大量的证据表明朊病毒是由PrPC错误折叠从而转变成PrPSc的,朊病毒病的发生与发展与PrPC转变成PrPSc密切相关,朊病毒病属于蛋白质构象病。本文将着重叙述PrPC转化成PrPSc的各种影响因素。
出处
《国外医学(病毒学分册)》
2005年第3期87-91,共5页
Foreign Medical Sciences(Section of Virology)
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