摘要
对３８３０名０～１４岁儿童中发生的２１９例高热惊厥进行了分析。其中１８例有家族遗传倾向，经统计学处理，一级亲属患病率与一般群体患病率相比有显著性差异（Ｐ＜０．０１）。一、二级亲属的遗传度各为７２．１５±２０．０２％、６０．５９±３８．１７％，其加权平均遗传度为６９．６６±１７．７３％，经分析认为高热惊厥的遗传方式可能为多基因遗传。
Two hundred and nineteen cases of febrile convulsion(FC) in 3 830 children under 14 were analysed.Among them genetic tendence was found in 18 pedigrees. The statistical analysis showed that the rate of FC in the first degree relatives was significantly higher than that in general people (P<0.01).The heritabilities of FC in the first and second degree relatives were 72. 15±20. 02% and 60. 59±38.17%,respectively, and the weighted mean heritabilities was 69. 66 ±17. 73%. These findings suggest that the heritable mode is mostly multiple gene inheritance.
出处
《中华医学遗传学杂志》
CAS
CSCD
北大核心
1994年第5期283-284,共2页
Chinese Journal of Medical Genetics
