卷烟厂女工尿尼古丁测定及其吸收干预措施

Urinary nicotine and intervention test for absorption ofnicotine in female workers in tobacco industry

为了全面评价卷烟厂工人在生产过程中接触烟草的水平，我们对５６名制丝车间非吸烟女工、６５名包装车间非吸烟女工及５４名果糖饮料厂非吸烟女工进行尿中尼古丁含量的测定，并对制丝车间摆把工种女工尼古丁吸收的干预措施效果进行研究。结果表明，制丝车间及包装车间女工工作结束时尿中尼古丁含量分别为４４．８±５，１ｎｇ／ｍｌ和９９±５４ｎｇ／ｍｌ，均显著高于对照组。制丝组女工工作结束时尿中尼占丁含量亦明显高于班前含量（１１．４±６．７ｎｇ／ｍｌ）。尼古丁吸收干预试验结果表明，工人上班时同时使用口罩、手套和在夏季开启通风设备对尼占丁的吸收均有良好的防护作用。

he concentration of urinary nicotine ofnonsmoking female workers, 56 from shreddingworkshop, 65 from packing workshop and 54 frombeverage factory (as controls), was deterniined, and in-tervention test for the absorption of nicotine was car-ried out in female workers from shredding workshop.The mean geometric concentration of urinary nicotineof shredding workers and packing workers at the endof shift was 44.8 ± 5. 1 ng / ml and 9.9 ± 5.4ng / ml, andwas significantly higher than that of the controls (1.0±1 .0ng / ml) (P < 0.01 ). The coneentration of urinarynicotine of shredding workers was significantly higherat the end of shift than preexposure period (11 .46 ±6.73ng / ml). The intervention test for the absorptionof nicotine showed that there were good protection effects for the absorption of nicotine when glove andmask were used simultaneously and ventilator wasused in summer.