肝癌高发区扶绥县饮用水诱变效应与肝癌发病率关系

Relationship between Mutagenic Effects of Drinking Water and Incidence of Liver Cancer in Fusui County──A Prevalent Area

应用蚕豆根尖微核技术研究了扶绥县饮用水的诱变活性与肝癌发病率关系。结果表明该县饮用塘水中存在染色体畸变的物质，这类物质在各种饮水类型的水样中所诱发的蚕豆根尖微核效应与当地居民肝癌发病率关系一致（γ＝０．８６，Ｐ＜０．０５），提示这些化学诱变剂的存在可能是导致肝癌高发的重要因素之一，从而为肝癌的饮水污染病因理论提供实验佐证。

elationship between mutagenic activity of drinking water and incidenee of liver cancer was stu-died in Fusui County with micronucleus technique in the root tips of vicia faba. Results showed there existed substance that caused chromosome aberration in the drinking pond water of Fusui County. Micronucleus effects on the root tips of vicia faba induced by the substance in different kinds of drink-ing water coincided with the incidence of liver cancer(γ=0.86, P<0.05).It suggested the existenee of these chemical mutants in the water may be one of the important factors that caused high incidene of liver cancer.It provided experimental evidence for the etiological theory of liver cancer caused by the pollution of drinking water.