接触三硝基甲苯对男工性激素水平的影响

Effects of Exposure to TNT on Sex Hormones in Male Workers

对河南两家工厂三硝基甲苯（ＴＮＴ）作业现场劳动卫生学调查结果表明，车间空气中ＴＮＴ浓度绝大多数超过最高容许浓度（１ｍｇ／ｍ￣３），并且皮肤污染严重。对３１名ＴＮＴ作业男工和３０名对照男工血清睾酮（Ｔ）、间质细胞刺激素（ＬＨ）和滤泡刺激素（ＦＳＨ）的测定结果表明，ＴＮＴ接触者血清Ｔ水平显著低于对照组（Ｐ＜０．０１），而血清ＬＨ和ＦＳＨ水平则高于对照组（Ｐ＜０．０１）。同时还发现，ＴＮＴ接触男工性功能减退，精液乳酸脱氢酶活性和锌含量低于对照组。

ield investigation on labour hygiene in two plants producing trinitrotoluene(TNT)in Henan Province showed most air TNT levels in the workplace exceeded national maximum allowable concen-tration(MAC 1mg/m￣3)and the skin of the workers exposed to TNT was severely contaminated.De-terminations of serum levels of sex hormones showed those of testosterone were lower、but those of interstitial cell-stimulating hormone (ICSH or LH) and follicle stimulating hormone(FSH)were higher in workers exposed to TNT than that in controls with statistical significance(P<0.01).