开胃素A在猪一些器官内的分布

Localization of orexin A in some porcine organs

目的:研究苏钟猪一些器官内开胃素(或增食因子)A(orexinA)的分布。方法:免疫组织化学法。结果:开胃素A免疫阳性细胞分布于猪睾丸、肾上腺、胰腺、小肠、甲状腺和胸腺等部位,睾丸间质、胰岛和小肠的粘膜固有层有大量免疫阳性细胞存在,而在肾上腺皮质、甲状腺和胸腺等部位仅有少量免疫阳性细胞分布。结论:猪一些器官内开胃素A的分布与人和其他动物的基本相似。首次报道了开胃素A在甲状腺和胸腺的分布,反映了开胃素在种系发生上的保守性,也说明存在种间差异。

Objective: To study the localization of orexin A in porcine organs. Methods: Immunohistochemistry was used. Results: Orexin-like immunoreactive (orexin-IR) cells were observed in the testis, adrenal gland, pancreas, small intestine, thyroid gland and thymus, with the majority in the interstitial substance of the testis, islet cells of the pancreas and the proper layer of the small intestine mucosa and with the minority in the adrenal cortex, thyroid gland and thymic cortex. Conclusion: Our results are similar to those obtained from human and other animals. It is firstly reported that there are orexin-IR cells in the thyroid gland and thymus, indicating the conservative of phylogeny and species difference.