危重病监护病房休克患者血乳酸浓度变化与预后的关系

The Change of Blood lactic Acidosis of Shock Patients in Intension Care Unit and its Relationship with Prognosis

目的探讨血乳酸在休克患者中的致病机制与预后关系。方法64例危重病监护病房休克患者分为两组,存活组(n=38)和死亡组(n=26),测定开始出现休克时、休克发生后12、24、48和72小时的血乳酸浓度,同时观察其APACHEII评分。结果死亡组的血乳酸水平和APACHEII评分明显低于存活组,两者呈正相关(γ=0.792),死亡组乳酸浓度升高的幅度亦高于存活组。结论危重病监护病房休克患者血乳酸浓度和病情严重程度呈正相关,其变化对判断病人的病情发展和预后有重要意义。

Objective To study the change of blood lactic acidosis of shock patients in Intension Care Unit and its relationship with prognosis. Methods A total of 64 cases with shock in Intension Care Unit were divided into Survival group (n=38) and Death group (n=26). The levels of serum lactic acidosis were measured in the beginning of shock, 12, 24, 48 and 72 hour. At he same time, the APACHEII score were evaluated. Results The levels of serum lactic acidosis and its increasing extent in Death group were higher than those in Survival group. APACHEII score was lower than those in Survival group. There was positively correlation with the levels of serum lactic acidosis and APACHEII score (γ=0.792). Conclusion The levels of serum lactic acidosis of shock patients in Intension Care Unit were positively correlative with serious degree of illness and played important role in estimation of development and prognosis of illness.