18例非功能性胰岛细胞瘤的诊治分析

Diagnosis and treatment of18cases of nonfunctioning islet cell tumors

目的:探讨非功能性胰岛细胞瘤的诊断和治疗方法.方法:对1986～2004年收治的非功能性胰岛细胞瘤18例进行回顾性分析.结果:B超、CT检查肿瘤定位准确率分别为88.9%(16/18)和86.7%(13/15).术前B超引导包块穿刺活检定性诊断准确率为90%(9/10).18例中良性14例,恶性4例.17例行手术治疗,治愈性切除率为94.4%(17/18).术后胰瘘发生率为23.6%(4/17).结论:B超、CT和术前B超引导包块穿刺活检是诊断本病的主要手段,手术切除是治疗本病的主要方法.

Objective:To explore the diagnosis and treatment of nonfunctioning islet cell tumors.Methods:18patients with nonfunctioning islet cell tumors admitted from1986to2004were analyzed retrospectively.Results:Accurate localization rate of pancreatic mass by ultrasound and CTexaminations were88.9%(16/18)and86.7%(13/15)respectively.The accurate character diagnosis rate of preoperative ultrasound-guided needle biopsy was90%(9/10).Of the18cases,14were benign and4were malignant.17patients were performed surgically.The curative reˉsection rate was94.4%(17/18).The occurrence rate of pancreatic leakage was23.6%(4/17).Conclusion:Ultrasound,CTand preoperative ultrasound-guided needle biopsy were main methods in the diagnosis of nonfunctioning islet cell tumors.Surgical resection was an effective method in the treatment of this disease.