注射用水溶性维生素在食管癌、贲门癌围手术期中的应用

The Application of Water-soluble for Injection Vitamin Therapy in Perioperative Esophageal Carcinoma and Carcinoma of Gastric Cardia

目的:探讨注射用水溶性维生素在食管癌、贲门癌围手术期支持治疗中的应用价值。方法:将80例食管癌、贲门癌围手术期患者随机均分为对照组和治疗组,前者单独应用全肠外营养(TPN),后者在TPN的基础上加用注射用水溶性维生素1瓶,1次/d,连用7d。结果:治疗给服药后4h内尿负荷试验中维生素B1、维生素B2、维生素C排出量明显高于对照组(P<0.01);IgG、IgA和IgM水平对照组治疗后无明显变化,而治疗组明显上升(P<0.01)。结论:水溶性维生素在食管癌、贲门癌围手术期营养支持中是十分必要的。

OBJECTIVE:To evaluate the application value of water-soluble vitamin for injection in the treatment of pe-rioperative esophagus cancer and carcinoma of gastric cardia.METHODS:80patients with esophagus cancer or carcinoma of gastric cardia were randomly divided into control group and treatment group,the control group were treated with total par-enteral nutrition(TPN)therapy only while the treatment group were treated with one bottle of water-soluble vitamin for in-jection,q.d.for7days besides the TPN therapy.RESULTS:The volume ejections of Vit B 1 ,Vit B 2 and Vit Vit C in the treatment group showed significantly higher than those of the control group from the urine loading tests after receiving drugs for4hours(P<0.01);No significant differences were found in IgG,IgA and IgM levels in the control group,however,the levels of IgG,IgA and IgM in the the Vitamin H group increased significantly(P<0.01).CONCLUSION:Water-soluble vitamin for injection is essential in the nutritional support therapy in the treatment of perioperative esophagus cancer and car-cinoma of gastric cardia.