Barrett食管癌51例报告

CARCINOMA ARISING IN BARRETT’S ESOPHAGUS AND REPORT OF 51 CASES

报告５１例Ｂａｎｅｔｔ食管癌的外科治疗效果，占同期食管癌切除总数的１０．２％。患者平均年龄８岁，主要就诊症状为吞咽困难。按ＰＴＮＭ分期，Ⅱ期１８例，占３５．３％；Ⅲ期２９例，占５６．９％；Ⅳ期４例，占７．８％。５１例均行食管部分切除、胃食管重建术。术后３０天死亡率为３．９％，１、２和５年生存率分别为４５．９％、２５．０％和１３．６％。Ⅱ期肿瘤５年生存率（２５．０％）明显高于Ⅲ＋Ⅳ期（４．５％），两者差异有显著意义（Ｐ＜０．０５）。肿瘤直径＜６ｃｍ＜或＞６ｃｍ者，５年生存率分别为２５．０％和０（Ｐ＜０．０５）。结果表明，术后长期生存率与临床分期及肿瘤大小等因素有密切关系。

Abstract Fifty-one patients with carcinoma arising in Barrett’s esophagus were treated surgically from1971 to 1990.This represented 10.2 % of all treated cases with esophageal carcinoma during the same period. The mean age was 63 years.The most common symptom was dysphagia. According to PTNM staging, 18 were stage Ⅱ, 24 stage Ⅲ and 4 stage Ⅳ. All patients were treated bysurgery. The 30-day hospital mortality was 3.9%. The one, two and five-year survival rates were45.9%, 25.0% and 1 3.6%,respectively. The 5-year survival rate was significant greater for stageⅡ(25.0%)than for stage Ⅲ+Ⅳ patients(4.5%),and for tumor length <6 cm(21.0%)thanfor tumor length >6 cm (0). The results indicate that the survival rate following resection is closelyrelated to the clinical stage and tumor size.