声门上型喉癌侵及会厌前间隙的研究

INVESTIGATION ON INVASION OF PREEPIGLOTTIC SPACE BY SUPRAGLOTTIC CARCINOMA

１００例喉连续切片分析结果表明，声门上型喉癌有６０％侵及会厌前间隙，侵入途径以破坏会厌软骨和甲会韧带者居多，其次是绕过会厌茎。声门上型喉癌累及会厌前间隙，与肿瘤的形态、周边生长方式和肿瘤分化程度有一定关系，随Ｔ分期增高，侵入会厌前间隙的机率增大。作者认为，声门上型喉癌易侵及会厌前间隙，与肿瘤原发部位的解剖及组织学特性有关。

Abstract This study,based on analysis of 100 whole- organ serial sections of the larynx,concluded that preepiglottic spaee invasion is involved in 60% of supraglottic carcinoma . The preepiglottic space is involved either by invasion thiough the adjacent strutures of the epiglottis,or morefrequently by destroying the epiglottic cartilage and the thyro epiglottic ligament。The preepiglottic space is involved mainly by epiglottic and epiglottic ventricular carcinomas,accounting for 95 % of invade the space。The involvement of preepiglottic space by supraglottic carcinoma is intimately related to the morphologic features, marginal growth patterns,and Tclassification。Ulcerative carcinoma is the conllnonest,accouting for 65 %。The incldenee of the infiltrative carcinomas is is the highest.With increase in T stage,the percentange of invasion of preepiglottic space is increased.We believe that the easy invasion of the preepiglottic space by the supraglottic carcinoma is due to the fact that the epiglottic and epiglttic ventricular carcinomas which account for 83 % of supraglottic carcinomas are located in front of the larynx。In addition,the carcinoma easily dystroys the epiglottic,cartilage and enters the preepiglottic space because the embyonic barrier which exists below the glottis and the perichondrium of the epiglottic cartilage is quite fragile.