骨骼畸形儿童的临床研究

The Clinical Study of Children Bone Deformity

目的探讨骨骼畸形与晚发性佝偻病(DR)的关系.方法采用病例对照,结合临床调查,检测了85例骨骼畸形儿童及50例健康儿童的血钙、血磷、碱性磷酸酶(ALP)、骨碱性磷酸酶(BALP)、X线.结果85例5～16岁骨骼畸形儿童的临床症状主要为多汗、肢体疼痛、肢体无力、肌肉痉挛;体征以鸡胸和X形腿为多见;血钙、血磷、碱性磷酸酶检测阳性率均低,BALP测定阳性率(BALP>250U/L)为14.1%,诊断为DR,并与对照组比较,差异有显著性意义(p<0.05).结论要重视骨骼畸形儿童的诊断及DR的诊断和防治工作.

ObjectiveTo explore the relationships of bone deformity and delayed rickets. MethodsWith cases contrast and clinical investigation,85 cases of bone deformity and 50 cases of healthy children were tested by serum calcium,phosphous,alkaline phosphatase,bone alkaline phosphatase(BALP)and X-ray inspection. ResultsIncreased sweating,limb pain,disability in limbs and muscular spasms were the main clinical symptoms of 85 cases of bone deformity,with the age of 5-16 years old. Pigeon breast and knock-knee were the more common signs. The positive reaction of serum calcium ,phosphous,alkaline phosphatase were all lower. The positive reaction of BALP(BALP>250U/L) was 14.1%.The diagnosis of delayed rickets was made. There was a significant difference between two groups (p<0.05). ConclusionsWe must be paid attention to the diagnosis of children bone deformity and the diagnosis and prevention of delayed rickets.