摘要
首次研究了超声波辐射和相转移催化相结合的技术在Ｒｅｉｍｅｒ－Ｔｉｍａｎｎ反应合成香兰素中的应用，并探讨了影响反应的各因素。实验表明：在固－液相条件下以ＰＥＧ－６０００为相转移催化剂，超声波辐射２ｈ，所合成的香兰素产率可达３９．２％。这与研究同类反应报道的最好结果比较，香兰素产率提高７．２％，合成反应时间缩短一半．
The application of synergistic technology of ultrasonic radiation and phase transfercatalysis in Reimer-Tiemann reaction was studied for the first time and the effect of factorson reaction was also investigated．By using PEG-6000 as PTC with 2 hours of ultrasonic ra-diation，vanillin was synthesized in 39．2％ yield in presence of solid-liquid phase. Not onlywas yield of vanillin 7．2％ higher but also the reacting time was half shortened in comparisonwith the best results of the study on the same reaction.
基金
湖南省科委科研基金
关键词
香兰素
超声波辐射
相转移催化
vanillin；guaiacol； ultrasonic radiation；phase transfer catalysis；Reimer-Tiemannreaction
