摘要
综述了DNA辐射损伤导致的细胞阻遏于G1期以及在该时期对DNA的修复活动,提出了较大剂量辐射诱导的三磷酸腺苷不足导致细胞凋亡的假说,并分析了细胞走向凋亡与修复的辨正关系。
DNA damage induced by irradiation, which makes the cell arrested at G_(1 )stage and DNA repair being activated in this stage, are summarized. It is proposed that the deficiency of adenosine triphosphate which is induced by the larger irradiation dose, induces cell apoptosis. And the relationship of cell selecting repair and apoptosis is also analyzed.
出处
《原子核物理评论》
CAS
CSCD
北大核心
2005年第2期225-228,共4页
Nuclear Physics Review
基金
中国科学院百人计划基金资助项目~~
关键词
P53
辐射
三磷酸腺苷
凋亡
p53
irradiation
adenosine triphosphate
apoptosis
