脑膜及小脑的血管性肿瘤免疫组织化学观察

IMMUNOHISTOCHEMICAL STUDY OF THE VASCULARTUMORS OF THE MENINGES AND CEREBELLUM

对脑膜及小脑血管性肿瘤２０例进行了石蜡切片的单克隆抗体波形蛋白（ｖｉｍｅｎｔｉｎ）、上皮细胞膜抗原（ＥＭＡ）、结蛋白（ｄｅｓｍｉｎ）、胶质纤维酸性蛋白（ＧＦＡＰ）、第８因子相关抗原（Ｆ－ⅧＲＡｇ）、溶菌酶（ｌｙｓｏｚｙｍｅ）、抗糜蛋白酶（α１－ＡＴ）的免疫组化染色观察。结果显示：①所有肿瘤均来源于间胚叶成分。②小脑的血管母细胞瘤不是神经外胚叶来源，也不是组织细胞源性。③脑膜的血管母细胞瘤及血管外皮细胞瘤不是蛛网膜帽状细胞来源。根据以上结果，作者认为上述肿瘤，与软组织发生的血管母细胞瘤、血管外皮瘤一样，都是血管源性的。

wenty vascular neoplasms of the meninges and cerebellum were examined immunohis- tochemically by use of the following antibodies : anti-vimentin , EMA, desmin , GFAP , F-Ⅷ RAg , lysozyme and , α1-AT to study on their histogenesis. The results revealed that ( 1 ) all these tumors originated from mesenchymal components , ( 2 ) cerebellar hemangioblastomas neither arose from neuroectodermal nor from histiocytic origin , and ( 3 ) meningeal heman- gioblastomas and hemangiopericytomas did not come from meningeal arachnoid cells. Accord- ing to the above findings the authors recognized that all these neoplasms of the meninges and cerebellum were hemangiogenic origin, assuming that they arose from soft tissues.