摘要
应用ＳＬＡＢ免疫酶标法在石蜡切片上半定量分析增殖细胞核抗原（ＰＣＮＡ）的表达与７３例胃癌患者预后的关系，探讨其临床应用价值。结果表明，以ＰＣＮＡ阳性细胞５０％为界线，阳性率＞５０％者术后生存期较短，５年生存率较低，而淋巴结转移率则较高。提示ＰＣＮＡ检测可作为胃癌预后判断的良好指征。
xpression of proliferating cell nuclear antigen (PCNA ) in 73 cases of gastric carcinoma and its relationship to prognosis were semiquantitatively analysed by SLAB immunohis- tochemical method , and its clinical application was explored. The results showed that the . patients with > 50% PCNA positive rate correlated to a decreased survival , but higher rate of lymph node metastasis than that with < 50% positive rate. Our data suggested that PC- NA can be regarded as a significant prognostic indicator in gastric carcinoma.
出处
《中山医科大学学报》
CSCD
1994年第4期274-277,共4页
Academic Journal of Sun Yat-sen University of Medical Sciences
基金
本校科研基金
关键词
增殖细胞核抗原
胃肿瘤
预后
proliferating cell nuclear antigen
stomach neoplasm
prognosis
