DXA骨密度仪在国内标一化回顾性研究

Retrospective study on standardization of BMD machines in China

目的由于各种骨密度测量仪器的厂家类别和型号的不同,国内各地骨密度测量结果不尽相同。为了得到各仪器之间换算公式,对国内相关文献进行回顾性研究,真实反映中国人标准化骨密度状况。方法检索自1994年至2004年10月期间国内所有中文期刊中发表的全文文献,摘录并对137 929例次中国女性骨密度测量数据,按照测量部位分类,应用SPSS统计软件,得出各类骨密度仪之间的换算公式。结果以国内最多使用的LUNAR-DRX-L型骨密度仪为代表,推算出下面换算公式。腰椎正位: LUNAR-DPX-L=NORLAND-XR×1．102+ 0．00137,LUNAR-DPX-L=LUNAR-ExPERT×0．991+0．0005,LUNAR-DPX-L=LUNAR-DPX-IQ× 1．025+0．0003,LUNAR-DPX-L=HOLOGIC-QDR4500×1．184+0．0281,LUNAR-DPX-L=HOLOG- IC-QDR2000×1．156+0．00048。股骨颈:LUNAR-DPX-L=NORLAND-XR×1．0377+0．00026,LU- NAR-DPX-L=LUNAR-EXPERT×0．965+0．00083,LUNAR-DPX-L=LUNAR-DPX-IQ×0．986+ 0．00031,LUNAR-DPX-L=HOLOGIC-QDR4500×1．142+0．00033,LUNAR-DPX-L=HOLOG- IC-QDR2000×1．126+0．00042,股骨的TROCH区:LUNAR-DPX-L=NORLAND-xR×1．137+ 0．0021,LUNAR-DPX-L=LUNAR-EXPERT×0．985+0．0124,LUNAR-DPX-L LUNAR-DP×4Q× 0．972+0．00024,LUNAR-Z-DPX-L=HOLOGIC-ODR4500×1．031+0．0001,LUNAR-DPX-L=HO- LOGIC-QDR2000×1．205+0．00019。因此,总的各个仪器之间换算公式为:LUNAR-DPX-L=NOR- LAND-XR×1．092+0．0012,LUNAR-DPX-L=LUNAR-EXPERT×0．980+0．00706,LUNAR-DPX-L= LUNAR-DPX-IO×0．994+0．00028,LUNAR-DPX-L=HOLOGIC-QDR4500×1．119+0．0094,LU- NAR-DPX-L=HOLOGIC-QDR2000×1．162+0．00036。结论对中国人进行测量的骨密度结果是可以通过一定的系数互换的。回顾性研究能够基本真实反映各个仪器之间的换算公式,有一定的可信性。可以通过这样的研究方法尝试建立中国人的标准化骨密度(sBMD)。

Objective To find out a conversion formula among many different kinds of BMD machines used in China in order to be able to analyze the exited data. Methods All full-text articles published in Chinese cultures since 1994 to October 2004 were retrospective collected. The BMD results of 137929 Chinese women were analyzed together according to different part of the bones. Results According to the results of LUNAR-DPX-L which is most popularly used , the following conversion formula was achieved: In lumbar post-anterior film, LUNAR-DPX-L=NORLAND-XR×1. 102 + 0. 00137, LUNAR-DPX-L=LUNAR-EXPERT×0. 991 + 0. 0005, LUNAR-DPX-L=LUNAR-DPX-IQ×1. 025 + 0. 0003, LUNAR-DPX-L=HOLOGIC-ODR4500×1. 184+0. 0281, LUNAR-DPX-L=HOLOGIC-QDR2000×1. 156+0. 00048. In femoral neck, LUNAR-DPX-L=NORLAND-XR×1.0377+0.00026, LU-NAR-DPX-L = LUNAR-EXPERT×0.965 + 0.00083, LUNAR-DPX-L=LUNAR-DPX-IQ×0.986 + 0.00031, LUNARJ-DPX-L=HOLOGIC-ODR4500×1.142 + 0.00033, LUNAR-DPX-L=HO LOGIC-QDR2000×1. 126 + 0. 00042, In femoral TROCH area. LUNAR-DPX-L=NORLAND-XR×1. 137 + 0. 0021,LUNAR-DPX-L=LUNAR-EXPERT×0. 985 + 0. 0124, LUNAR-DPX-L=LUNAR-DPX-IQ×0. 972 +0. 00024, LUNAR-DPX-L=HOLOGIC-QDR4500×1. 031 + 0. 0001, LUNAR-DPX-L=HOLOGIC-QDR2000× 1. 205+0. 00019. The conversion formula were: LUNAR-DPX-L=NORLAND-XR×1. 092 + 0. 0012, LUNAR-DPX-L=LUNAR-EXPERT×0. 980 + 0. 00706, LUNAR-DPX-L = LUNAR-DPX-IQ×0. 994 + 0. 00028, LUNAR-DPX-L = HOLOGIC-QDR4500×1. 119 + 0. 0094, LUNAR-DPX-L= HOLOGIC-QDR2000×1.162 + 0. 00036. Conclusions The conversion formula between different BMD machines makes it possible to set up a Chinese standard bone mineral density.