二甲双胍与阿卡波糖分别联合胰岛素治疗2型糖尿病的最小成本分析

Comparison of Cost-minimization Analyses between Metformin and Acarbose Combined with Insulin in Treating Type2Diabetes Mellitus

目的:比较二甲双胍与阿卡波糖分别联合胰岛素治疗2型糖尿病的效果和成本。方法:运用药物经济学最小成本分析法,从病人角度出发,对治疗效果、成本及成本的影响因素进行分析。结果:2种治疗方案疗效之间的差异无统计学意义。二甲双胍组人均治疗总成本为1941 46元,药物成本为138 .86元;阿卡波糖组人均治疗总成本为2308 .37元,药物成本为229 .82元。成本的影响因素分析显示无统计学意义。结论:二甲双胍组治疗方案相对较优。

OBJECTIVE:To compare the effects and costs between metformin and acarbose when combined with insulin in treating type2diabetes mellitus.METHODS:Cost-minimization analysis in medical economy was applied to analyze the therapeutic effects,costs and cost related factors with the respect for the patients.RESULTS:There was no statistically sigˉnificant difference in effects of the2therapeutic regimens.Total cost and drug cost per head in metformin group were1941.46yuan and138.86yuan respectively as compared with2308.37yuan and229.82yuan respectively in acarbose group.The analysis on cost related factors showed no statistical significance.CONCLUSION:Metformin combined with insulin is a preferable therapeutic regimen.