羧酸衍生物的烯醇盐的立体选择性氧化二聚反应

Stereoselective Oxidative Dimerization of Carboxylate Enolates

综述羧酸衍生物的烯醇盐氧化二聚成键的规律,重点是立体选择性的过程。近期进展是利用手性辅助试剂,如各种不同的手性酯和手性酰胺不对称合成立体专一性的1,4-二羰基化合物,为不对称合成琥珀酸衍生物提供了有效方法。

Stereoselective oxidative dimerization of the enolate of carboxylic acid derivatives is summarized focusing on the stereoselectivity of the process. Recent developments making use of chiral auxiliaries such as chiral esters, hiral acylimidazolidinones and chiral butyryloxaxolidines have put forward the versatility of procedure for the asymmetric synthesis of 1, 4-dicarbonyl compounds, which constitutes a useful procedure for the asymmetric synthesis of succinic acid derivatives.