复肝肽致畸效应的研究

Study of Hepar-recovered's Peptide (HRP) on Deformation

70年代初期,LaBrecque、Goldberg、Strarl、Russell、同部和彦、谢明、陈光明等陆续从大鼠、狗再生肝、人胎肝、乳猪肝中提取出一种小分子多肽,认为此物质有促进肝细胞DNA合成和肝脏再生的功效。临床证实,对重症肝炎、肝硬化都有较好的疗效。复肝肽为我单位从乳猪肝中提取的同类多肽,在急性毒性实验的基础上,我们对它进行了致畸效应的研究。 一。

HRP is a hepatic regenerative stimulator substance producted by our academy from suckling pig liver. During pregnancy, mice were injected with HRP. Many results suggested that HRP do not induce deformation in mice.