十二指肠溃疡穿孔单纯修补术后加用药物治疗的远期疗效

Long-term Therapeutic Results in Patients with Perforated Duodenal Ulcer Operated on by Simple Closure and Pharmacal Management

目的确定十二指肠溃疡穿孔单纯修补术+口服H2受体阻滞剂和(或)质子泵抑制剂或抗幽门螺杆菌(HP)等药物治疗的远期效果.方法对宣武医院1991年1月至2000年12月序贯收治的77例十二指肠溃疡穿孔单纯修补术+口服H2受体阻滞剂等药物的出院病人进行随访.结果随访到65例患者,术后溃疡症状复发率(VisickⅢ～Ⅳ)为15.4%(10/65)、再穿孔手术率为1.5%(1/65);40例复查内镜者复发7例(17.5%).结论十二指肠溃疡穿孔修补术加H2受体阻滞剂或质子泵抑制剂及抗HP治疗的远期效果较满意.

Objective To investigate the long-term follow up results of patients with duodenal ulcer perforation managed by simple suture and pharmacal management. Methods All discharged patients (77 patients) with perforated duodenal ulcer consecutively operated on with simple closure underwent follow-up in our hospital from January 1991 to December 2000. According to follow-up data, the long-term results of recurrence of ulcer symptoms for these patients with perforated duodenal ulcer operated on with simple closure were determined. Results The rate of symptomatic ulcer recurrence (VisickⅢ～Ⅳ) and Existing rate of ulcer of postoperative patients with endoscopy examination in four to eight weeks were 15.4%(10/65), 17.5%(7/40) respectively, and reoperation rate was 1.5%(1/65). Conclusion The long-term results indicated that it had a good effect to prevent the recurrence of ulcer symptoms that H_2 receptor antagonists and proton pump inhibitors and drugs of anti-helicobacter pylori were used in patients with perforated duodenal ulcer operated on with simple closure.