心衰灵治疗慢性心衰的临床观察

Clinical Observation on Chronic Heart Failure Treated with Xinshuailing,

心衰灵为一中药复方,临床治疗慢性心衰21例,治疗后患者的症状体征有明显改变,总有效率为90.4％,心功能得到提高者占90.5％,心率及心功能检查几项主要指标的变化.经统计学处理,均有显著意义(P<0.01)。心衰灵对Langendorff大鼠心脏灌流实验研究结果表明,心衰灵可使心脏搏动持续时间延长(P<0.01),可使心脏停搏后至复跳时间缩短(P<0.01),而且作用结果超过阳性对照药哇巴因。

Twenty - one cases of chronic heart failure were treated with Xinshuailing, a compound recipe consisting of Chinese drugs. After the therapy, all patientswere markedly improved in signs and symptoms, with a total effective rate of 90. 4%. 90. 5% of the cases were improved in their heart functions. The changes in the indices of heart rate a'nd heart functions were all significant statistically (P<0. 01). By experimental heart infusion in Langendorff rats, itwas shown that Xin-shuailing prolonged the time of heart beat (P<0. 01), andshortened the interval between standstill and resuscitation of heart beat (P<0. 01), with its action excelled that of ouabin as a positive control.