营养不良并贫血患儿红细胞体积分布宽度的变化

Changes of red blood cell volume distribution width in children with malnutrition and anemia

目的探讨营养不良并贫血患儿红细胞体积分布宽度(RDW)的变化及其临床意义。方法将中、重度营养不良并贫血患儿63例设为观察组,30例门诊健康体检儿童设为对照组,分别取静脉血检测RDW、血红蛋白、红细胞数量、红细胞平均容积(MCV)、红细胞平均血红蛋白量(MCH),并进行对照比较。结果63例营养不良并贫血患儿存在大细胞性贫血、正细胞性贫血和小细胞性贫血,3种类型贫血患儿的RDW差别不明显(P>0.05),但均较对照组明显升高(P<0.01)。结论营养不良并贫血患儿可发生明显的RDW改变,RDW是早期诊断营养不良并贫血有效的检测方法之一。

Objective To investigate the changes of red blood cell volume distribution width (RDW) and its clinical significance in children with malnutritional and anemia.Methods The RDW was detected and analysed in 63 children who were suffered from moderate or severe malnutrition complicated with anemia.The control group included 30 children who were out-patient health examination.The hemoglobin(Hb),red blood count(RBC),mean corpuscular volume (MCV),mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC) and RDW were detected in both groups.Results According to the MCV、MCHC,the children of malnutritional anemia were devided into three types of anemia including macrocytic anemia,normocytic anemia and microcytic anemia.There was no significant difference in RDW among three types of anemia.The RDW in malnutrition group was more significantly elevated than that in control group(P<0.01).Conclusion RDW is of great importance in diagnosing malnutritional anemia.